Busting Covid myths on plasma therapy and remdesivir
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In the past few weeks, several questions have been raised around various Covid treatments including plasma therapy and the anti-viral drug remdesivir, which is part of India’s Covid treatment protocol. ThePrint’s Editor-in-Chief Shekhar Gupta busted three Covid-related myths — on plasma therapy and remdesivir.

Confusion regarding REMDESIVIR:

• “The logic is remdesivir’s action is to reduce viral replication,” Gupta said. When our body attempts to fight the virus, it can get overwhelmed. Remdesivir could reduce the rate of viral replication so the number of virus in our bodies remains smaller.

• Both steroids and anti-virals are needed at different points in the disease. “The current view is that the time for anti-viral is in the first week…The time for steroids is in the second week, if you need it, and doctors make that choice in the hospital,” Gupta said.

• If remdesivir is used in the second week, by that time our body doesn’t have the virus so it is not cutting down on any viral infection.

• Similarly, if steroids are used early in the infection, then they block our body’s immune reaction too early and it isn’t able to fight the virus and the virus keeps replicating.

Breaking down misconceptions on PLASMA THERAPY

• “If plasma therapy isn’t working, it means antibodies don’t work. Then, how come monoclonal antibodies work because the principal is the same, that your body gets these antibodies as a reinforcement to fight the virus,” Gupta said.

• There are two kinds of antibodies — normal antibodies and neutralising antibodies, The latter is key to the plasma therapy process.

• Each patient who has recovered from coronavirus and has antibodies in their plasma may not necessarily have neutralising antibodies. In order to use that plasma, one should be able to separate neutralising antibodies (which is the principal followed by monoclonal antibodies).

• Therefore, plasma therapy can be effective if it is used after checking for neutralising antibodies.

Source: https://theprint.in/opinion/busting-covid-myths-on-plasma-therapy-and-remdesivir-and-what-indias-falling-numbers-mean/531501/
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Dr. L●●l S●●●●●a General Medicine
Conditional approch to plasma the thrapy.is OK
Nov 10, 2020Like