COVID-19 In Heart Failure Patients Tied To Increased Risk Of
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Mount Sinai researchers found that COVID-19 patients with a history of heart failure were associated with a longer duration of hospitalization, nearly three times the risk of intubation and mechanical ventilation, and double the risk of death, compared to those without a history of heart failure.

This study described the clinical profile and associated outcomes among patients with HF hospitalized with COVID-19.

Researchers conducted a retrospective analysis of 6,439 patients admitted for COVID-19 between February 27 and June 26, 2020. Clinical characteristics and outcomes (length of stay, need for intensive care unit, mechanical ventilation, and in-hospital mortality) were captured from electronic health records. For patients identified as having a history of HF by International Classification of Diseases-9th and/or 10th Revisions codes, manual chart abstraction informed etiology, functional class, and left ventricular ejection fraction (LVEF).

Mean age was 63.5 years, and 45% were women. Compared with patients without HF, those with previous HF experienced longer length of stay (8 days vs. 6 days), increased risk of mechanical ventilation (22.8% vs. 11.9%), and mortality (40.0% vs. 24.9%). Outcomes among patients with HF were similar, regardless of LVEF or renin-angiotensin-aldosterone inhibitor use.

Conclusively, history of HF was associated with higher risk of mechanical ventilation and mortality among patients hospitalized for COVID-19, regardless of LVEF.