COVID-19-associated central retinal vein occlusion treated w
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Retinal findings following infection with SARS-CoV-2 virus occur due to complement activated thrombotic microangiopathy and hypercoagulable state. This can lead to retinal artery and venous occlusions. There are a few papers on retinal vein occlusion associated with COVID-19 infection in literature. Authors report a case of central retinal vein occlusion (CRVO) and macular oedema associated with COVID-19 infection. The highlight of this case is the improvement in visual acuity and macular oedema following reversal of hypercoagulable state with oral antiplatelet therapy.

This is a case report of central retinal vein occlusion (CRVO) associated with COVID-19 treated with oral aspirin therapy. A 56-year-old woman reported decreased vision in her left eye. Her left eye vision was 6/18, N10. Anterior segment was within normal limits. Left eye fundus was suggestive of CRVO and macular oedema. Optical coherence tomography showed cystoid macular oedema and neurosensory detachment. Blood work-up revealed elevated D-dimer levels and erythrocyte sedimentation rate (ESR).

She was started on treatment with low-dose aspirin 150 mg/day. After 1 month, her vision improved to 6/6, N6. Left eye fundus showed reduced retinal haemorrhages and complete resolution of macular oedema. Her repeat blood work-up showed reduced D-dimer and ESR levels. The patient was asked to be reviewed after 3 months. This case highlights that specific treatment for reducing the hypercoagulable state caused by COVID-19 with oral aspirin therapy can result in complete resolution of CRVO macular oedema.

Source: https://casereports.bmj.com/content/14/5/e242987?rss=1
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