CT promising for sublobar resection in early-stage non-small
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According to an article in ARRS' American Journal of Roentgenology (AJR), CT features may help identify which patients with stage IA non-small cell lung cancer are optimal candidates for sublobar resection, rather than more extensive surgery.

This retrospective study included 904 patients (453 men, 451 women; mean age, 62 years) who underwent lobectomy (n=574) or sublobar resection (n=330) for stage IA non-small cell lung cancer. Two thoracic radiologists independently evaluated findings on preoperative chest CT, later resolving any discrepancies. Recurrences were identified via medical record review.

"In patients with stage IA non-small cell lung cancer, pathologic lymphovascular invasion was observed only in solid-dominant part-solid nodules and solid nodules with solid portion diameter over 10 mm," concluded the corresponding author.

"Among such nodules," the authors of this AJR article continued, "peritumoral interstitial thickening and pleural contact were independently associated with pathologic lymphovascular invasion." Moreover, models incorporating these features independently predicted recurrence-free survival after sublobar resection.

Source: https://www.ajronline.org/doi/10.2214/AJR.21.25618
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