Calcium supplements linked to earlier death in older people
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Researchers tracked the heart health of 2657 patients (average age 74;42% women) with mild to moderate aortic stenosis between 2008 and 2018: the average monitoring period was more than 5.5 years.

Participants were divided into those not taking any supplements (1292;49%), those supplemented with vitamin D alone (332;12%), and those given calcium plus or minus vitamin D supplements (1033;39%),115 of whom took just a calcium supplement.

Those taking supplements had significantly more diabetes and coronary artery disease than those not taking supplements. They were also more likely to be taking statins, warfarin, and phosphate binders (to limit phosphorus absorption), to have had a coronary artery bypass graft and to need kidney dialysis.

During the monitoring period, 540 (20.5%) people died:150 died of cardiovascular disease; 155 died of other causes; and 235 died of unknown causes. And 774 (29%) people had their aortic valve replaced. More than a third of people in each of the groups developed severe aortic stenosis after 5 years.

Calcium supplements, frequently given to older people to lessen the risk of brittle bones (osteoporosis) and fractures, are linked to a heightened risk of death among those with aortic valve stenosis, a progressive and potentially fatal condition.

Source: https://heart.bmj.com/content/early/2022/03/23/heartjnl-2021-320672
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