Carbohydrates and fibre from fruits and vegetables protects
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Inconsistent findings have been reported on the link between dietary carbohydrates and lung cancer. This study aims to comprehensively evaluate the role of dietary carbohydrates on lung cancer risk.

The prospective study is based on the PLCO trial, which recruited 113,096 eligible participants across the United States. Participants had to have completed baseline and diet history questionnaires. The incidence of lung cancer was acquired through self-report and medical record follow-up. A multivariable logistic model adjusted for confounders was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) of dietary carbohydrates, fiber, whole grains, glycemic index (GI) and glycemic load (GL) for lung cancer. Similar methods were applied in analyzing the carbohydrates and fiber from different food sources.

-- Dietary carbohydrates and GL were inversely associated with lung cancer incidence in the PLCO population.

-- Among various carbohydrates, 30-gram daily consumption of dietary fiber was related to a lower risk of lung cancer compared with 8.8-gram.

-- Furthermore, consuming whole grains 2.3 servings per day as opposed to 0.3 servings per day was associated with a lower risk of lung cancer.

-- A higher risk of lung cancer was seen for the consumption of high-GI food and refined carbohydrates from soft drinks.

Conclusively, Carbohydrates and fiber from fruits, vegetables and whole grains are associated with lower lung cancer risk. Refined carbohydrates from processed food, such as soft drinks, appear to increase risk.