Cardiac transport system linked to better outcomes after hea
The study compared survival and other postoperative outcomes in heart transplant recipients who received a heart delivered with the cardiac transport system with those whose hearts were delivered in traditional cold storage. The cohort included 569 adult patients who received their hearts from October 2015 to January 2022; those who received the cardiac transport system and those who received cold storage were matched based on propensity scores.

The rate of survival at 1 year was 96.4% in the cardiac transport system group compared with 88.7% in the cold storage group (difference, 7.7 percentage points; P = .03). The cardiac transport system was also associated with a 71.9% reduction in rates of severe primary graft dysfunction (3% vs. 12%; P = .005), a 38.5% reduction in posttransplant mechanical circulatory support (P = .03), a 66.3% reduction in use of extracorporeal membrane oxygenation or a ventricular assist device (P = .02) and a 59.7% reduction in newly placed intra-aortic balloon pumps (P = .02) compared with traditional cold storage, according to the researchers.

The results of this study suggest that using ice to preserve and transport donor hearts is a potentially inferior method for organ preservation. A 96.4% 1-year survival rate in the propensity-matched analysis utilizing the SherpaPak is an encouraging sign that this technology for advanced organ preservation is having an impact on the clinical outcomes of heart transplantation.