Changes in B-type Natriuretic Peptide Following a Fluid Chal
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Sepsis is among the top ten causes of death.It is defined as a systemic inflammatory response syndrome of infectious origin. Progression results in severe sepsis, with the failure of one or more organ systems. Further progression leads to septic shock. Death in septic patients has been suggested to be due to multiple organ failures (MOF).The mortality of septic shock may be as high as 50%. While treating the underlying cause of sepsis is important, symptomatic organ support is vital. This includes fluid resuscitation and vasoactive drugs to prevent MOF.The decision to give more fluid or to initiate vasoactive agents remains challenging, with inadequate or excessive treatment associated with suboptimal outcomes. The aim of this study is to examine the effect of a fluid challenge on the B-type natriuretic peptide (BNP) and the hemodynamic state.......

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363098/
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