Cheilitis and gingivitis as first signs of Crohn's disease i
The present case has been published in the journal Clinical Case Reports. A 12‐year‐old child was referred for a diffuse gingivitis of the maxilla of several month duration, persistent after scaling and full‐mouth disinfection.

The patient showed also angular cheilitis, lip fissuring, oral mucosal tags, cobblestoning mucosa, while extra‐oral findings were abdominal pain and frequent diarrhea.

A gingival biopsy was performed showing the presence of noncaseating granulomas that suggested the necessity of colonoscopy with bowel biopsy.

The final diagnosis was Crohn's disease (CD) with gingival onset. The complete healing of the gingival lesions was observable after few months of systemic therapy with anti‐inflammation and immune suppressive drugs.

Key clinical message:-
- Oral manifestations of Crohn's disease include gingivitis, deep ulcerations, pseudopolyps, and labial or buccal swelling; these are uncommon in children and can precede or coincide intestinal inflammation lesions, leading frequently to a delayed diagnosis.

Read more here:
1 share