Chorioamniotic membrane separation caused by the seromucinou
Placental chorioangioma is a rare and benign non-trophoblastic tumor of the placenta originating from primitive chorionic mesenchyme [1]. Most of these tumors are small and asymptomatic; however, large tumors can occur and these have side effects on both, the mother and fetus, such as fetal anemia, hydrops, polyhydramnios, preterm delivery, fetal growth restriction and fetal demise [2,3,4].

Chorioamniotic membrane separation (CMS) is rare condition of detachment between the amniotic membrane and chorionic membrane. CMS may cause premature rupture of membrane, preterm delivery, amniotic band syndrome, or strangulation of the umbilical cord. In severe cases, it can lead to fetal distress and intrauterine fetal death [5]. It can occur after invasive fetal procedures such as fetal surgery and amniocentesis, or it may occur spontaneously; spontaneously occurring CMS is associated with fetal abnormalities [6].

Here, we report a case of a large placental chorioangioma with cystic changes within the tumor and profuse seromucinous fluid collection, which was possibly associated with the cause of CMS.

Case report
A 29-year-old woman (gravida 2 and para 1) was referred to our fetal-maternal division at 30+4 weeks of gestation for evaluation of polyhydramnios. There was no remarkable personal and familial history. Ultrasound examination revealed a single fetus with vertex presentation and growth within the normal range for gestational age (1,774 g, 60th percentile). There was no evidence of fetal hydrops or other fetal structural abnormalities. There was polyhydramnios and amniotic fluid index was 58 cm. The placenta was anteriorly placed in the uterus. We found a 4.84×6.33-cm-sized mixed solid and cystic mass with high vascularity within the left lateral placenta and suspected it as a placental chorioangioma....

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