Chronic lymphocytic leukemia skin infiltration mimicking an
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"This article presents a case report on an unreported and unusual cutaneous manifestation of chronic lymphocytic leukemia in a patient with an implantable cardioverter-defibrillator (ICD).

Case presentation
A 65-year-old man with a history of chronic lymphocytic leukemia (CLL), previously treated with chlorambucil, was referred in October 2013 for extraction of a single chamber ICD due to a suspected device-related infection in the pulse generator area. The ICD system had been implanted in November 2009. The patient complained of painless erythema with pruritus in the pocket area. Inflammatory blood parameters were C-reactive protein 17.3 mg/L and leucocytes 29.0 × 109/L. Due to the atypical appearance of the pocket area the device was not extracted. Instead, an exploratory excision was created in the skin induration, which had been present for approximately 6 weeks, and conducted a microbiological and histological examination. All cultivation examinations were negative. However, histologically show skin infiltration was done by CD-5 positive low-grade B-cell chronic lymphocytic leukemia. Re-initiation of chemotherapy was not necessary and the skin induration completely disappeared within 2 months.".....

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