Chronic recurrent multifocal osteomyelitis: case series from
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare auto-inflammatory disease of the bone. It tends to be multifocal and usually the symptoms tend to run for months and years before diagnosis is usually made.

The objective of the present study, published in the Indian Journal of Orthopaedics was to understand the clinical presentation and short-term response to treatment of CRMO patients. A retrospective analysis of patients diagnosed with CRMO was done. Case records of these were retrospectively reviewed for clinical features, investigations and treatment received.

Six patients were diagnosed with CRMO. The median age of onset and time to diagnosis from onset of symptoms was 8 and 3.5 years respectively. Lower limb bones were the most commonly involved.

The authors concluded that there is significant delay in diagnosis of CRMO and this could be because of a lack of awareness of this condition amongst clinicians.

This case series with only male affection is rather unique as compared to other case series reported in medical literature which tend to have more female predilection. Pain with or without swelling was the most common symptom. Most of patients responded to combination therapy.

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