Cicatrizing conjunctivitis as an uncommon manifestation of p
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To report the occurrence of cicatrizing conjunctivitis as an extraglandular ocular manifestation of primary Sjögren's syndrome a study was conducted. Medical charts of all patients with Sjögren's syndrome evaluated at two tertiary ophthalmological referral centers were reviewed. Patients who demonstrated clinical findings of cicatrizing conjunctivitis were included in this review. Patient and disease-related data including ocular complications, therapies, and outcomes were collected.

Eight patients with a diagnosis of Sjögren's syndrome were noted to have cicatrizing conjunctivitis findings over a period of 11 years. The mean age of patients was 79. All patients had a negative immunoreactant deposition in the conjunctival biopsy. Mean follow-up time was 6 years. Three patients had progression of conjunctival scarring. Worsening of vision occurred in 4 patients due to corneal complications, including ulceration, perforation, and scarring.

Sjögren's syndrome is an under-recognized etiology of severe progressive cicatrizing conjunctivitis that can lead to ocular morbidity and loss of vision without appropriate management.

Source:https://www.sciencedirect.com/science/article/abs/pii/S154201242030183X
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