Ciliary Body Mass as a Feature of Ocular Sarcoidosis
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Ocular sarcoidosis may be the primary and only clinical manifestation of sarcoidosis, and irreversible loss of visual acuity may occur from delayed treatment. Thus, early diagnosis is imperative to preserve visual acuity. Establishing the diagnosis of sarcoidosis in cases manifesting only in the eye may require a diagnostic biopsy, which may prove challenging in the absence of available ocular surface, lacrimal gland, and systemic tissue for biopsy

Here is a study published in JAMA Dermatology ,the patients were a 52-year-old woman, a 42-year-old man,and an 81-year-old man. Two individuals had unilateral involvement, and 1 had bilateral involvement. All 3 individuals presented with uveitis. Diffuse, circumferential ciliary body masses were observed in 2 patients. A localized, nodular ciliary body mass on the temporal quadrant with superior and inferior extensions was observed in 1 patient. Moderate to high internal reflectivity was observed on ultrasonographic biomicroscopy in all 3 individuals. Biopsies of the ciliary body masses were diagnosed as sarcoidosis in all 3 patients.

Conclusively, these findings support that diffuse or segmental ciliary body mass may serve as a clinical sign and tissue source for biopsy in the diagnosis of ocular sarcoidosis, although the frequency of this cannot be determined from 3 cases. Such cases all demonstrate a uveitic component; whether a ciliary body mass caused by sarcoidosis can occur in the absence of uveitis remains unknown.

Key Points:

Question
-How was ocular sarcoidosis associated with diffuse or segmental ciliary body mass in 3 patients with uveitis without previously known systemic sarcoidosis?

Findings
- Biopsies of the ciliary body mass, identified via ultrasonographic biomicroscopy, were diagnostic of ocular sarcoidosis in the 3 patients without previously known systemic sarcoidosis.

Meaning
-Diffuse or segmental ciliary body mass could be a clinical sign of ocular sarcoidosis, although the frequency of this association could not be determined.

Source: https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2760493
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