Clapping-surpressed focal spikes in EEG may be unique for th
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Rett syndrome is classically characterized by early normal development for at least the first 6 months of life, followed by a period of regression and later recovery or Stagnation. The main features of typical Rett syndrome include a partial or complete loss of purposeful hand skills, development of hand stereotypies, partial or complete loss of spoken language and gait abnormalities.

This article reports one child diagnosed with Rett syndrome, with a specific electroencephalogram (EEG) feature that continuous centrotemporal spikes can be suppressed by the repeated hand clapping. The purpose of this report is to present a novel, rarely reported EEG characteristic, which may also aid diagnosis.

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