Clinical Diversity of Cerebral Sinovenous Thrombosis and Art
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In neonates, arterial ischaemic stroke (AIS) and cerebral sinovenous thrombosis (CSVT) have different relative risks, risk factors, clinical appearance, onset of symptoms, and age at diagnosis. Clinically, distinguishing these two entities in time can be critical.

In 345 German paediatric hospitals, active surveillance for AIS and CSVT was carried out. This research only looked at cases that were confirmed by a cerebral MRI. In terms of age at diagnosis, clinical symptoms pattern, and risk factors, AIS patients were compared to CSVT cases.

Results:
--Data on 144 AIS and 51 CSVT neonatal cases were collected. The relative risk of AIS was 2.8 times higher than that of CSVT.

--CSVT patients were more likely to be born premature (CSVT 14/48, 29.2%; AIS 19/140, 13.2%) and to have signs of perinatal acidosis.

--Generalized seizures and lethargy were more likely to occur in infants with CSVT.

--Age at onset of symptoms and at time of diagnoses was shifted to older ages in CSVT.

In neonates, the chance of AIS is approximately three times higher than that of CSVT. Since CSVT has a higher proportion of critically ill babies and symptoms occur later, perinatal and postnatal risk factors may be more important for CSVT than for AIS. The findings highlight the importance of raising CSVT awareness among critically ill babies.

Source: https://www.karger.com/Article/Abstract/512526
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