Clinical Presentation and Features of SARS-CoV-2 Infection i
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Among 171 confirmed cases, common symptoms were cough, pharyngeal erythema and fever, while 16% were asymptomatic. To identify the clinical features and short-term outcomes of SARS-CoV-2 infection in children, researchers described cases treated in Wuhan, China, the epicenter of the current pandemic.

Of 1391 children assessed between January 28 and February 26, 2020, 171 children (12%) were confirmed to have SARS-CoV-2 infection: 60% were boys, the median age was 7 years, and age ranged from 1 day to 15 years. Twenty-seven (16%) of the confirmed cases were asymptomatic without pneumonia.
Clinical features included the following:

-The most common symptoms were cough (49%) and fever (42%).

-Fever >39o C occurred in 9% of confirmed cases.

-Less-common features were diarrhea, fatigue, rhinorrhea, vomiting, and nasal congestion.

-Pneumonia was present in 111 children, including 12 who were asymptomatic.

-Blood tests were unremarkable except for lymphopenia in 6 children.

-Computed tomography (CT) appearance of pneumonia included a ground-glass opacity in 33% of cases.

-Three children required intensive care with mechanical ventilation; all had a chronic underlying health condition.

-One 10-month-old child died after 4 weeks of hospitalization.

These data add to our understanding of how SARS-CoV-2 infection, which causes COVID-19, may appear in children. Children do seem to have a less-severe clinical course in general, as other early data suggest. However, the findings of asymptomatic pneumonia and ground-glass features on CT raise a concern about the prospect of long-term pulmonary morbidity and indicate that we need to follow pulmonary function even in children with asymptomatic infections. We must do everything we can to reduce the spread of this epidemic.

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