Co-existing malakoplakia and xanthogranulomatous pyelonephri
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Xanthogranulomatous pyelonephritis (XGP) and malakoplakia (MKP) are both chronic infective condition of the kidney. Host responses to chronic infection result in characteristic pathological lesions. MKP is characterized by periodic acid-Schiff (PAS) positive Michaelis–Gutmann bodies, whereas XGP is characterized by PAS negative, otherwise both the disease share similar gross and microscopic features. Rarely, they may co-exist. We present such an unusual case of MKP and XGP co-existing in the same kidney. This indicates that it may be the different spectrums of the same disease process...

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