Coexistent intracerebral metastatic melanoma and meningioma
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Melanomas and meningiomas are tumors of neural crest origin. Their coexistence is termed as neurocristopathy. We report a case of parietal lobe meningioma existing with a metastatic melanoma in the frontal lobe. Multifocal neural crest tumors necessitate a thorough radiological examination for investigating the presence of a neurocristopathy. A 50-year-old woman complained of a headache and slurred speech since the past 1 month. She had chronic hypertension and was on anti-hypertensive therapy. Subsequently, the frontal mass was resected in toto without any vascular damage. Histopathology showed a highly cellular tumor. Cells showed abundant brownish pigment, nuclear pleomorphism, brisk mitoses, and tumor necrosis. Thus, a diagnosis of malignant melanoma was made.

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