Coffee consumption link to reduced risk of acute kidney inju
AKI is a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days. AKI symptoms differ depending on the cause and may include: too little urine leaving the body; swelling in the legs and ankles, and around the eyes; fatigue; shortness of breath; confusion; nausea; chest pain; and in severe cases, seizures or coma. The disorder is most commonly seen in hospitalized patients whose kidneys are affected by medical and surgical stress and complications.

Using data from the Atherosclerosis Risk in Communities Study, an ongoing survey of cardiovascular disease in four U.S. communities, researchers assessed 14,207 adults recruited between 1987 and 1989 with a median age of 54. Participants were surveyed seven times over a 24-year period as to the number of 8-ounce cups of coffee they consumed per day: zero, one, two to three, or more than three. During the survey period, there were 1,694 cases of acute kidney injury recorded.

When accounting for demographic characteristics, socioeconomic status, lifestyle influences and dietary factors, there was a 15% lower risk of AKI for participants who consumed any amount of coffee versus those who did not. When adjusting for additional comorbidities—such as blood pressure, body mass index (BMI), diabetes status, use of antihypertensive medication and kidney function—individuals who drank coffee still had an 11% lower risk of developing AKI compared with those who did not.

Those who drank any quantity of coffee every day had a 15% lower risk of AKI, with the largest reductions observed in the group that drank two to three cups a day (a 22%–23% lower risk).