Complete congenital heart block: A case of multilevel block
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Congenital heart block (CHB) has long been associated with maternal anti-SSA/Ro antibodies. Injury to the conduction system is presumed to be a consequence of the transplacental passage of maternal IgG autoantibodies into the fetal circulation.Within the heart, a spectrum of phenotypes has been described, including structural defects, functional abnormalities and electrical disturbances such as heart block. Third-degree atrioventricular (AV) block is typically irreversible, has a mortality rate approaching 30%, and requires pacemaker placement in up to 66% of cases.We describe a newborn with complete CHB in the setting of maternal anti-SSA/Ro antibodies in whom interatrial dissociation was recognized after placement of a dual-chamber epicardial pacemaker system with bipolar LA and left ventricular (LV) pacing leads....


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