Complications in one-third undergoing total laryngectomy
The researchers found that complications occurred in 83 patients (33.9 percent), including three deaths (1.2 percent). Fifty-three patients (21.6 percent) had wound complications, and 34 were pharyngocutaneous fistulas (PCFs, 13.9 percent overall). Readmission within 30 days occurred in 34 patients (13.9 percent). In multivariate analysis, wound complications were associated with former and current smokers (odds ratios, 5.1 [P = 0.03] and 5.8 [P = 0.02], respectively); PCFs correlated with prior wide-field, but not prior narrow-field radiation (odds ratios, 3.1 [P = 0.01) and 1.4 [P = 0.61], respectively); length of stay correlated with the type of flap and postoperative hematomas (P = 0.002 and 0.05, respectively); and readmission correlated with preoperative hypoalbuminemia and postoperative wound complications (P = 0.003 and P < 0.001, respectively)

http://medicalxpress.com/news/2017-01-complications-one-third-total-laryngectomy.html
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