Concurrent diagnosis of giant cell arteritis and chronic lym
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Multiple reports have suggested an association between vasculitis and hematologic malignancies, but most have involved small or medium-sized vasculitides.In this case study, we describe the unique finding of 2 simultaneous disease processes, giant cell arteritis and chronic lymphocytic leukemia, on temporal artery biopsy. A 76-year-old male presented with a 2-month history of scalp tenderness and bitemporal pain that occurred episodically over several years. He denied any visual symptoms, jaw claudication, amaurosis fugax, diplopia, arthralgia, myalgia or loss of appetite or weight, but confirmed occasional night sweats, which began several weeks before his visit. Relevant medical history included hypertension, cerebrovascular accident, and stable thoracoabdominal aneurysm. Histologic findings showed intimo-medial fibrosis and loss of the internal elastic lamina, consistent with healing arthritis. Notably, some lymphocytes were noted in the tissue surrounding the artery suggesting the presence of a lymphoproliferative disorder, such as B-cell CLL or small lymphocytic lymphoma.

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