Corneal Collagen Cross-Linking in Pellucid Marginal Degenera
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Pellucid marginal degeneration (PMD) is a rare, idiopathic, bilateral, progressive noninflammatory thinning corneal disorder. It is characterized by a peripheral band of thinning, usually occurring in the inferior quadrant in a crescentic fashion. This study involved the retrospective analysis of 4 eyes of 2 patients with PMD that underwent CXL treatment. Of the eyes, three had only CXL treatment and one had CXL treatment after an intrastromal corneal ring segment implantation. This article evaluates pre- and postoperative uncorrected distance visual acuity (UDVA), best-corrected distance visual acuity (BCDVA), corneal topography (Pentacam), specular microscopy, and pachymetry.

Patient 1 was a woman, aged 35, and Patient 2 was a man, aged 33. The right eye of Patient 1 showed an improvement in her BCDVA, from 16/40 to 18/20 in 15 months, and her left eye improved from 12/20 to 18/20 in 20 months. Patient 2’s right eye showed an improvement in his BCDVA, from 18/20 to 20/20 in 43 months, and his left eye improved from 16/20 to 18/20 in 22 months. No complications were recorded during or after the treatment.

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