Coronary CT angiography: Beyond morphological stenosis analy
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Introduction:
Coronary artery disease (CAD) is the leading cause of death in advanced countries and its prevalence is increasing among developing countries. Traditionally, diagnosis of CAD is performed by invasive coronary angiography which is considered the gold standard technique, since it has superior spatial and temporal resolution leading to excellent diagnostic accuracy. However, it is an invasive and expensive procedure associated with a small but distinct procedure-related morbidity (1.5%) and mortality (0.2%). Furthermore, invasive coronary angiography usually requires patients to stay for a short period in the hospital after the examination and this causes discomfort for the patients. Thus, a non-invasive technique for imaging and diagnosis of CAD is highly desirable.

Cardiac imaging has experienced rapid growth in recent years. Several techniques have been investigated for diagnosis and prognosis of patients with proven or suspected CAD. Although currently there is no less-invasive imaging modality that can replace invasive coronary angiography, the development of computed tomography (CT), magnetic resonance imaging (MRI), single photon emission computed tomography and positron emission tomography contribute to the detection and diagnosis of CAD less invasively when compared to the invasive coronary angiography.....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879698/
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