Coronavirus infectiousness wanes by day 9: UK Study
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Infected by the coronavirus may not be capable of transmitting the virus after 9 days, according to a new study reported in medRxiv on 27 July and is awaiting peer review.

Key Insights:

• Mean SARS-CoV-2 RNA shedding duration in the upper respiratory tract, lower respiratory tract, stool and serum were 17.0, 14.6, 17.2 and 16.6 days, respectively.

• Maximum duration of SARS-CoV-2 RNA shedding reported in URT, LRT, stool and serum was 83, 59, 35 and 60 days, respectively.

• No study to date has detected live virus beyond day nine of illness despite persistently high viral loads.

• SARS-CoV-2 viral load in the upper respiratory tract appears to peak in the first week of illness, while SARS-CoV-1 and MERS-CoV peak later.

• SARS-CoV-2 RNA shedding in respiratory and stool can be prolonged, duration of viable virus is relatively short-lived. Thus, detection of viral RNA cannot be used to infer infectiousness.

• High SARS-CoV-2 titres are detectable in the first week of illness with an early peak observed at symptom onset to day 5 of illness.

This review underscores the importance of early case finding and isolation, as well as public education on the spectrum of illness.

Source: https://www.medrxiv.org/content/10.1101/2020.07.25.20162107v2
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