Covid reinfection: Man gets Covid twice and second hit 'more
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A 25-year-old man in the United States has caught Covid twice, with the second infection becoming far more dangerous than the first, doctors report.

The man from Nevada had no known health problems or immune defects that would make him particularly vulnerable to Covid.

What happened when:

• 25 March - First wave of symptoms, including sore throat, cough, headache, nausea and diarrhoea

• 18 April - He tests positive for the first time

• 27 April - Initial symptoms fully resolve

• 9 and 26 May - He tests negative for the virus on two occasions

• 28 May - He develops symptoms again, this time including fever, headache, dizziness, cough, nausea and diarrhoea

• 5 June - He tests positive for the second time and is hypoxic (low blood oxygen) with shortness of breath

Scientists say that a comparison of the genetic codes of the virus taken during each bout of symptoms showed they were too distinct to be caused by the same infection.

So far, reinfection seems to be rare - there have been only a few examples out of more than 37 million confirmed cases.

Reports in Hong Kong, Belgium and the Netherlands said they were no more serious than the first. One in Ecuador mirrored the US case in being more severe, but did not need hospital treatment.

It is still unclear why the Nevada patient become more severely ill the second time. One idea is he may have been exposed to a bigger initial dose of the virus. It also remains possible that the initial immune response made the second infection worse.

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