Cuff Leak Test Good at Ruling In Post-Extubation Airway Obst
Because of its high specificity, a cuff leak test is better at ruling in than ruling out post-extubation airway obstruction in adults who are mechanically ventilated, a meta-analysis has concluded.

The analysis of 21 studies included 3,772 patients and was presented at the 2018 annual meeting of the Society of Critical Care Medicine. Although it has excellent specificity, the moderate sensitivity of the cuff leak test (CLT) may mean other options with higher sensitivity to predict post-extubation airway obstruction may be preferred.

“Our systematic review of 21 diagnostic accuracy studies found that the sensitivity and specificity of the cuff leak test to predict post-extubation laryngeal edema was 69% and 89%, respectively,” the lead author of the study has said.

The 2017 American Thoracic Society (ATS) and American College of Chest Physicians (ACCP) clinical practice guideline recommends performing a CLT when liberating critically ill patients from mechanical ventilation to separate those at high risk for post-extubation airway events because prophylactic corticosteroids are indicated for these patients.

Read more here: