Deceased donor chain initiating kidneys might increase annua
Simulations revealed that using deceased donor kidneys in transplant chains could increase the number of transplants by 290 a year, according to data published in the Kidney International Reports.

Investigators noted that using deceased donors (DD) can increase transplantations for blood type O kidney-paired donation (KPD) candidates. Researchers simulated strategies to allow DD to initiate KPD chains based on 2016 and 2017 U.S. DD and waitlist data. The KDP pools, however, were simulated with LDs and high proportions of highly sensitized and/or blood type O candidates.

Using the simulations, researchers tested six strategies designed with a “view to ease of implementation, and in each case fewer than 3% of the total national number of DD kidneys are allocated to the KPD pool.”

Analyses revealed longer DD initiated chains increased the number of KPD transplants by up to 5% and lowered the number of DDs granted to the KPD pool by 25% compared with shorter DD-initiated KPD chains. According to the study, allocating less than 3% of DD to start KPD chains could lead to 290 more kidney transplants a year.

Source: https://www.kireports.org/article/S2468-0249(22)01243-8/fulltext
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