Decompression retinopathy after intravitreal bevacizumab and
Case Report
A 56-year-old female with type II diabetes, who had been previously diagnosed with bilateral proliferative diabetic retinopathy accompanied with NVG, presented with visual disturbance in his left eye. The best-corrected visual acuity (BCVA) was 20/25 in the right eye and 20/400 in the left eye. The intraocular pressure (IOP) was 11 mmHg in the right eye and 47 mmHg in the left eye despite treatment with both topical dorzolamide/timolol fixed combination and brimonidine twice a day. The left pupil was fixed (4 mm) and non-reactive to light. Slit-lamp examination showed active iris neovascularization and mild nuclear sclerosis in the left eye. Fundus examination of the left eye showed a hazy view due to corneal edema . We immediately injected intravitreal bevacizumab (1.25 mg/0.05 ml) and performed an anterior chamber paracentesis with a 30-gauge needle in her left eye. No deformation of the globe occurred during the procedure, and the IOP immediately dropped to 10 mmHg in the left eye. One day later, IOP was 22 mmHg and the corneal edema was much resolved. Multiple retinal hemorrhages scattered throughout the posterior pole were revealed in his left fundus examination. After a 1-month follow-up period, IOP was increased to 35 mmHg. We performed an Ahmed valve implantation combined with cataract surgery in the left eye. Over the next 2 months, the BCVA improved to 20/50 and IOP was controlled at 14 mmHg without any IOP-lowering medication. The multiple retinal hemorrhages gradually faded without sequelae.

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