Dedifferentiated Chondrosarcoma of Proximal Tibia and Fibula
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Chondrosarcoma (CS) is a low-grade malignant bone tumor whereas DDCS is a highly malignant, fatal tumor despite aggressive surgical resection or amputation. DDCS accounts for 10% of all chondrosarcomas. The presence of multiple types of tumor cells poses a challenge to the treatment and radical surgical resection remains the primary treatment modality. Lung metastasis is found early in the disease and is often the main reason for treatment failure and death in DDCS. In early stages, the tumor may be treated with radical resection or limb salvage surgery, but amputation is often necessary when there is extensive local tissue destruction or secondary infection. We report a case of dedifferentiated chondrosarcoma of proximal tibia and fibula with a discharging ulcer in a 51-year-old male patient.

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