Degenerative Cervical Spondylosis- A comprehensive review by
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Degenerative cervical spondylosis is a chronic, progressive deterioration of osseocartilaginous components of the cervical spine that is most often related to aging. Radiographic evidence of degeneration of the cervical spine occurs in virtually all persons as they age; however, not all persons have the typical symptoms of neck pain or neurologic deficits that correspond to the mechanical compression of neural elements.

Symptomatic cervical spondylosis is initially managed with nonsurgical treatment options, which usually result in abatement of symptoms. Surgical intervention may be indicated if there is clinically significant dysfunction or progressive instability or deformity of the cervical spine. No currently approved therapy addresses the cause of degenerative cervical spondylosis or reverses the deterioration. In select patients, surgical intervention can lead to favorable outcomes.

The goals of surgery are to decompress the nerve roots or spinal cord and stabilize the spine, while attempting to restore or maintain relatively normal spinal alignment. Outcomes depend on the severity and duration of the neurologic deficit at the time of surgery. Advanced age, smoking, and coexisting conditions such as obesity and diabetes mellitus have been shown to negatively affect outcomes.

Source: https://www.nejm.org/doi/full/10.1056/NEJMra2003558?query=featured_surgery
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