Desmoplastic fibroma of femur with atypical image findings
Desmoplastic fibroma of the bone (DFB) is an extremely rare benign bone tumor, which can occur in any bone at all ages. Published in the journal Medicine, the authors report a similar case with non-specific imaging findings.

A 25-year-old female patient reported with repeated pain in the right thigh lasting over 1 year. The patient reported to have had right thigh pain and swelling 1 year ago, accompanied by limitation of motion (LOM), which was relieved after rest.

In the following year and thereafter, the patient felt pain and swelling in the right thigh when catching a cold, which was mitigated by rest and was thus long neglected. Approximately 1 week ago, the patient had this right thigh pain again, but this time it apparently aggravated more than ever before.

X-ray revealed an uneven density in the distal left femur, in which lamellate high-density opacity and bone destruction were observed. Furthermore, the CT findings indicated proximal femoral thickening with irregular, low-density opacity, and a long-axis parallel that was to the femur. The well-defined lesion had an even soft tissue density as well as the hardening strap.

MRI findings revealed massive and lamellate uneven long T1 and short T2 signals in and around the distal left femur, which were ill-defined with the surrounding muscular part, and local femoral cortex signal was non-continuous. A lesion with an approximate size of 6.5 cm × 13.7 cm was identified that had been compressing the quadriceps femoris; a continuous signal in the tendon was obtained.

Histopathology was suggestive of desmoplastic fibroma of the femur. Wide surgical resection was performed. At the 1-year follow-up visit, no relapse in the tumor was observed.

Key words:-
In this case report, the authors described and emphasized the particularity of the case examined and the possible non-specificity of the imaging results of some DFB cases.

Read in detail here: