Detecting change using standard global perimetric indices in
Various global indices are available to summarize results from standard automated perimetry. This study asks which index can detect significant deterioration earliest, for a fixed specificity.

The median time to detect significant deterioration with MD was 7.3 years (95% confidence interval 6.8–7.9 years). For VFI, the median was 8.5 years (7.9–9.0); this comparison had p=0.088. For PSD, the median was 10.5 years (9.3–11.7); slower than MD with p<0.001. Within the first five years of a series, MD detected significant deterioration in 138 eyes, versus 104 for VFI (p=0.0013) and 107 for PSD (p=0.029).