Determinants of severe bradycardia in adolescents hospitaliz
A Study was conducted to define the prevalence of severe bradycardia as the cause for hospital admission in adolescents with AN and to evaluate the average time required to recover from severe bradycardia after re-feeding. Some adolescents with anorexia nervosa (AN) and significant weight loss present with a normal pulse rate at admission, whereas others have severe bradycardia, suggesting that total weight loss is not the most important determinant of bradycardia.

99 hospitalized patients with AN were analysed. Multivariate analysis was performed to detect the most important determinants of severe bradycardia.

--48% of the AN patient admissions were due to severe bradycardia.

--Patients in this group had a higher maximum lifetime weight, greater premorbid weight loss, and more rapid weight loss.

--Multivariate analysis showed that recent weight loss is an independent predictor of bradycardia at hospital admission.

--Severe bradycardia normalized after minimal weight gain of 0.25±0.18 Kg/day for 3 to 10 days.

Conclusively, research shows that recent weight loss is likely the most important driver of severe bradycardia in adolescents with AN.