Diabetic Ketoacidosis and Mortality in People With Type 1 Di
This study aimed to determine the risk of diabetic ketoacidosis (DKA) and all-cause mortality among adolescents and young adults with type 1 diabetes with and without an eating disorder.

With use of population-level health care administrative data covering the entire population of Ontario, Canada, all people with type 1 diabetes aged 10–39 years were identified. Individuals with a history of eating disorders were age- and sex-matched 10:1 with individuals without eating disorders. All individuals were followed for 6 years for hospitalization/emergency department visits for DKA and for all-cause mortality.

-- Researchers studied 168 people with eating disorders and 1,680 age- and sex-matched people without eating disorders.

-- Among adolescents and young adults with type 1 diabetes, 168 (0.8%) had a history of eating disorders.

-- The crude incidence of DKA was 112.5 per 1,000 patient-years in people with eating disorders vs. 30.8 in people without eating disorders.

-- After adjustment for baseline differences, the subdistribution hazard ratio for comparison of people with and without eating disorders was 3.30.

-- All-cause mortality was 16.0 per 1,000 person-years for people with eating disorders vs. 2.5 for people without eating disorders. The adjusted hazard ratio was 5.80.

Conclusively, adolescents and young adults with type 1 diabetes and eating disorders have more than triple the risk of DKA and nearly sixfold increased risk of death compared with their peers without eating disorders.

Source: https://care.diabetesjournals.org/content/early/2021/06/25/dc21-0517?rss=1