Diagnostic Ability of OCTA Macula Vessel Density for the Dia
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There is diagnostic information in the outer region of optical coherence tomography angiography (OCT-A) macula scans not available in the inner region, and this information is especially useful in the early stages of glaucoma. The aim of this study was to evaluate the diagnostic accuracy of 3×3 and 6×6 mm2 macula OCT-A scans for classifying healthy, mild glaucoma, and moderate to severe glaucoma eyes.

Two hundred seventy-nine eyes (89 healthy, 127 with mild glaucoma, and 63 with moderate to severe glaucoma) from 190 subjects were included in this study. The VD of the outer area of the 6×6 mm2 scan size had higher diagnostic accuracy compared with the VD of the inner area of the 3×3 mm2 scan when differentiating between healthy and mild glaucoma . The VD of the outer area of the 6×6 mm2 scans had only similar diagnostic accuracy compared with the inner area of the 3×3 mm2 scan when differentiating between healthy and moderate to severe glaucoma eyes. The VD of the inner area of the 6×6 mm2 scan size had similar diagnostic accuracy to the corresponding area of the 3×3 mm2 scan in both diagnostic categories.

In conclusion the diagnostic accuracy of VD using the 6×6 mm2 macula OCT-A scan was better than the 3×3 mm2 scan when differentiating between healthy and mild glaucoma eyes, and similar to the 3×3 mm2 scan when differentiating between healthy and moderate to severe glaucoma eyes.

Source: https://journals.lww.com/glaucomajournal/Abstract/2020/04000/Diagnostic_Ability_of_Optical_Coherence_Tomography.2.aspx
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