Diagnostic value of triglyceride and cystatin C ratio in diabetic kidney disease: a retrospective and prospective cohort study based on renal biopsy - BMC Nephrology
Background Currently, there is a lack of clinical indicators that can accurately distinguish diabetic kidney disease (DKD) from non-diabetic kidney disease (NDKD) in type 2 diabetes. The purpose of th
The clinical data of patients with type 2 diabetes complicated with proteinuria who underwent renal biopsy were retrospectively collected. According to the pathological classification of kidneys, 25 patients in group DKD and 34 patients in the non-diabetic kidney disease (NDKD) group were divided into two groups. A retrospective study showed that compared with group NDKD, the DKD group had higher systolic blood pressure, higher cystatin C and creatinine, more diabetic retinopathy, longer duration of diabetes, lower hemoglobin concentration, lower glomerular filtration rate, lower cholesterol, lower triglyceride and lower TG/ Cys-C ratio (P<0.05). Multivariate Logistic regression analysis showed that TG/Cys-C ratio (OR=0.429, P=0.009) was a protective factor for DKD in patients with type 2 diabetes and proteinuria. Diabetic retinopathy (OR=7.054, P=0.021) and systolic blood pressure (OR=1.041, P=0.047) were independent risk factors for DKD in patients with type 2 diabetes complicated with proteinuria.
Source: https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-022-02888-3
Source: https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-022-02888-3
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