Dietary Patterns is linked with Risk of Developing Knee Oste
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The association between dietary factors and risk of knee osteoarthritis (OA) have been reported earlier. Researchers aimed to examine the prospective association of major dietary patterns with the risk of developing knee OA.

Researchers followed 2,842 participants in Osteoarthritis Initiative (OAI) aged 45 to 79 years and with at least one knee free from radiographic knee OA at baseline for up to 72 months. Knee OA incidence was defined as Kellgren and Lawrence grade more than 2 during follow-up visits. Using principal component analysis, Western and prudent dietary patterns were derived. Cox proportional hazards models were used to assess the association between dietary patterns and incident knee OA.

Results:
--Among study participants, 385 developed knee OA within 72 months.

--Following a Western dietary pattern was associated with an increased risk of knee OA (HR quartile 4 vs 1 = 1.69), while adherence to the prudent pattern was associated with a reduced risk of knee OA (HR quartile 4 vs 1 = 0.70).

--The observed associations attenuated after additionally adjusting for body mass index (BMI).

--The observed associations were mediated through BMI by approximately 30%.

In conclusion, eating a Western diet was linked to an increased risk of knee OA, while eating a prudent diet was linked to a lower risk of knee OA. BMI was found to play a role in the associations.

Source: https://www.sciencedirect.com/science/article/abs/pii/S1063458421006361?dgcid=rss_sd_all
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