Disc Rehydration after dynamic stabilization: A report of 59
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The intervertebral disc (IVD) is the most important stabilizing and load-bearing structure in the spinal column and is also among the main causes of back pain. IVD consists of two parts: the annulus fibrosus (AF) and the nucleus pulposus (NP). AF comprises fibrocartilaginous and fibrous connective tissues, whereas NP primarily consists of proteoglycans. In IVDs, most fibrils comprise types 1 and 2 collagens, and aggrecan is the dominant proteoglycan. Proteoglycans, which are hydrophilic in nature, maintain adequate disc turgor, thereby allowing the radial distribution of compressive loads. A degenerated disc cannot self-regenerate. In addition, long-term elevated or impaired intradiscal pressure prevents regeneration. However, distraction or stabilization may provide suitable conditions for rehydration and, therefore, regeneration. Several studies have suggested that dynamic stabilization systems (DSSs) can provide these suitable conditions. Therefore, our study aimed to evaluate clinical outcomes and disc regeneration via MRI in a series of patients with degenerative disc disease (DDD) who underwent lumbar stabilization with DSS.

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