Disrupted Sleep Linked To Higher Risk Of Death, Especially I
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A new study has shown a clear link between the frequency and duration of unconscious wakefulness during night-time sleep and an increased risk of dying from diseases of the heart and blood vessels, and death from any cause, particularly in women.

The study of 8001 men and women found that female adults who experienced unconscious wakefulness most often and for longer periods of time had nearly double the risk of dying from cardiovascular disease during an average of between 6 and 11 years' follow-up when compared to the risk in the general female population.

The association was less clear in men, and their risk of cardiovascular death increased by just over a quarter compared to the general male population. Researchers looked at data from sleep monitors worn overnight by men and women taking part in one of three studies: 2782 men in the Osteoporotic Fractures in Men Sleep Study (MrOS), 424 women in the Study of Osteoporotic Fractures (SOF), and 2221 men and 2574 women in the Sleep Heart Health Study (SHHS). The average ages in the studies were 77, 83 or 64 years, respectively.

The participants were followed up over a period of several years, which ranged from an average of six years (SOF) to 11 years (MrOS). The researchers found that women had an arousal burden that was lower than men. But those who had arousal burden accounted for more than 6.5 percent of their night's sleep had a greater risk of dying from cardiovascular disease.

Taking the women from both studies together, those with an arousal burden of more than 6.5 per cent had a 12.8 per cent risk of dying from cardiovascular disease. Men with an arousal burden accounting for more than 8.5 per cent of their night's sleep had 1.3 times greater risk of dying from cardiovascular disease (MrOS) or any cause (SHHS), compared to men with lower arousal burdens.

The triggers causing an arousal or the body's response to arousal may differ in women compared to men. This may explain the relatively higher risk of cardiovascular death in women. Women and men may have different compensatory mechanisms for coping with the detrimental effects of arousal.

Source:
https://www.escardio.org/The-ESC/Press-Office/Press-releases/Disrupted-sleep-is-linked-to-increased-risk-of-death-particularly-in-women
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