Disrupted sleep has small effect on youth depressive symptom
Sleep disruption had a small but statistically significant impact on depressive symptoms among children and youths, according to results of a systematic review and meta-analysis published in JAMA Network Open.

In the current study, researchers aimed to assess the link between depression and disturbed sleep among children and adolescents.

They searched six databases and included prospective cohort studies published between 1980 and August 2019 that reported estimates, adjusted for baseline depression, of the link between disturbed sleep and depression among participants aged 5 to 24 years from the community and clinical-based samples with any comorbid diagnosis. Sleep disturbances or insomnia comprised disturbed sleep, which was the main measure. Age, sex, and sociodemographic variables served as covariates. The researchers included 22 studies, with 28,895 patients, in the overall study, and 16 studies, with 27,073 patients, in the meta-analysis.

Results showed a pooled beta coefficient of 0.11 for the association between disturbed sleep and depression. Those with disturbed sleep vs. those without had a pooled OR of depression of 1.5. Pooled estimates did not appear to differ across any covariate, according to meta-regression and sensitivity analyses.

“Although the pooled effect sizes are small, the high prevalence of children and youths with disturbed sleep implies the existence of a large cohort of vulnerable individuals who could develop depression,” the author wrote. “Disturbed sleep could be one of the many risk factors to address in depression prevention programs. Randomized clinical trials targeting disturbed sleep as early as childhood are needed to inform the planning and evaluation of depression prevention programs. These findings must be considered in the context of the limitations and the overall very low quality of evidence of the included studies.”

Source: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2777741?resultClick=3
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