Duodenal complications in necrotizing pancreatitis: Challeng
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Duodenal complications of necrotizing pancreatitis (NP) are challenging and understudied. Researchers sought to characterize the demographics and clinical course of NP patients with duodenal complications.

In this retrospective review of 647 patients with necrotizing pancreatitis, 6% of patients experienced duodenal complications.

Duodenal complications developed in 40 (6%) patients including fistula in 11 (2%) and stricture in 29 (4%) patients. Patients with duodenal complications had increased computed tomography severity index (CTSI), degree of glandular necrosis, organ failure, infected necrosis, and disease duration. Mortality from NP was increased in patients with duodenal fistula (36%) compared to patients with duodenal stricture (7%) and patients without duodenal complications (9%). Surgical management of duodenal complications was required in 9/11 (82%) patients with fistula and 17/29 (59%) patients with a stricture.

Duodenal complications occurred in 6% of necrotizing pancreatitis patients. Sixty-five percent of patients with duodenal complications required surgical correction. The duodenal fistula was associated with increased mortality.

Source:https://www.americanjournalofsurgery.com/article/S0002-9610(20)30745-5/fulltext?rss=yes
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