E-Cigarettes and Methemoglobinemia: A Wolf in Sheep’s Clothi
First developed in 2003, since then e-cigs have become a popular smoking-cessation tool amongst the smokers. Just over a decade since their commercialized use, e-cigs are already under scanner for its ill effects. The Centers for Disease Control and Prevention (CDC) states that additional research is required to know the long-term side effects of e-cigs.

Recent studies have revealed deleterious health effects in both acute and chronic settings, including increased risk of pneumonia, tissue hypoxia, and lung injury.

In a case discussed in literature, a young female seemed to be overwhelmed by the ongoing emotional stress and multi system disorders. No further recurrence of cyanosis strongly favored e-cig as the potential cause of methemoglobinemia. Rare chemicals like paint thinners, naphthalene ball etc have been reported to cause methemoglobinemia. It is important to remember that even topical agents, such as dapsone ointment, can cause methemoglobinemia.

Currently there are close to 8000 e-liquid formulations for commercial use. What is more frightening is that only a few of them have been tested for toxicity in the laboratory.

There is too much hype among youngsters about the e-cigs as an efficient smoking-cessation tool. A recent pilot study demonstrated no benefit in reducing the craving to smoke in e-cig-naive users. Similarly, another recent study has found a significant association between youngsters with childhood maltreatment and lifelong addiction to e-cigs. To conclude, until we know better about long-term ill-effects, e-cigs use should not be promoted as also suggested by FDA.

source: https://www.amjmed.com/article/S0002-9343(19)30544-3/fulltext?rss=yes
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