ESRD Risk Higher in SLE Patients Hospitalized for Infections
Infection-related hospitalizations are associated with a significantly higher risk of end-stage renal disease (ESRD) in patients with systemic lupus erythematosus (SLE), according to researchers. The risk is particularly elevated in patients with juvenile-onset SLE.

In a nationwide cohort study of 7326 SLE patients in Taiwan, Chien-Hung Lin, MD, of the National Yang-Ming University in Taipei, and colleagues found that patients who had 3 or more infection-related hospitalizations had a 5-fold increased risk for ESRD compared with those who experienced no infection-related hospitalizations. Among patients diagnosed with SLE before age 18 years, those with 3 or more infection-related hospitalizations had a 14-fold increased risk.