Early Intervention for the Laryngeal injury after Intubation
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A recent JAMA study suggests that early intervention in laryngeal injury after intubation may disrupt the natural course of this disease, minimize fibrotic scar formation, and limit long-term physiological impairment.

This study by JAMA Otolaryngology-Head & Neck Surgery was aimed to compare functional outcomes between early and late intervention for intubation-related laryngeal injury.

This retrospective cohort study involved 29 patients with a laryngeal injury resulting from endotracheal intubation. Ten patients with intubation injury to the posterior glottis who received early treatment were compared with 19 patients presenting with posterior glottic stenosis who received late treatment.

The result showed;

--Nine of 10 patients who received early intervention and 11 of 19 patients who received late interventions were decannulated at the last follow-up.

--Patients who received early treatment required fewer total interventions than patients with mature lesions.

--In addition, none of the patients who received early treatment required an open procedure, whereas 17 patients with mature lesions required open procedures to pursue decannulation.

In conclusion, early intervention for patients with post-intubation laryngeal injury was associated with a decreased duration of tracheostomy dependence, a higher rate of decannulation, and fewer surgical procedures compared with late intervention. Patients with early intervention also avoided open reconstruction.

Source: https://jamanetwork.com/journals/jamaotolaryngology/article-abstract/2775609