Early diagnosis of diabetic peripheral neuropathy based on i
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The purpose of this study was to detect and compare the surface temperature of plantar vessels in mild DPN patients and healthy controls, to explore a simple, convenient and reliable method for early diagnosis of DPN, and to explore the influence of gender and age on vascular surface temperature.

In this study, 60 mild DPN patients (30 males and 30 females) were randomly recruited, and 60 healthy volunteers were recruited according to their age and gender. ICC3,1 was used to evaluate the repeatability of skin temperature measurement in vascular area. General linear model was used to analyze the difference of skin temperature between mild DPN patients and healthy controls.

Results
-- The infrared detection results of skin temperature corresponding to blood vessels showed excellent test?retest reliability.

-- There was no significant difference in skin temperature between gender and age.

-- Except for the posterior tibial artery, there were significant differences in skin temperature between mild DPN patients and healthy controls.

Conclusively, for mild DPN patients, in the case of lower extremity artery corresponding skin temperature infrared detection does not indicate obvious abnormality, small vessels have appeared early abnormal body surface temperature, that is, the increase of skin temperature of related vessels. The conclusion of this study can provide an in vivo, noninvasive and convenient method for early diagnosis of DPN.

Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/dmrr.3429?af=R
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