Early prenatal diagnosis of conjoined twins: a case report
Published in the International Journal of Reproduction, Contraception, Obstetrics and Gynecology, the authors report a case of conjoined thoraco-omphalopagus twins, diagnosed by ultrasonography at 10 weeks of gestation. Due to high complexity of fetal fusion, termination of pregnancy was performed upon patient's request.

A 33-year-old woman, gravida 2 para 1, was referred to fetal medicine unit at 10 weeks of gestation for suspected conjoined twins after a routine ultrasound examination. Her past medical history was unremarkable, there was no family history of twins and the actual pregnancy was a spontaneous conception. Present ultrasound (US) revealed a monochorionic monoamniotic twin pregnancy with two fetuses in a fixed face-to-face position.

Two heads were visualized, and two upper and two lower limbs were seen for each fetus. There was no change in the relative positions of the fetuses despite attempts. The twins were found to be joined at the thorax and upper abdomen, and only one fetal heart seemed to be observed. Both fetuses had cystic hygroma.

On the base of these findings, the diagnosis of thoracoompalopagus twins was made. The couple was informed about US findings and counselled on the management options. They opted for termination of pregnancy, which was performed medically within one week.

The autopsy confirmed the diagnosis: two fetuses fused from the upper thorax to umbilicus. Two hearts were present, but they shared the stomach, liver, pancreas and bowel. Fetus 1 had oesophagal atresia and absent right lung and fetus 2 had a complete atrioventricular canal defect. Gonads were not identified. Analysis showed a 46, XX karyotype.

Read in detail here: https://pxmd.co/uzvP6
Dr. N●●●●●●. B P●●●l and 4 others like this