Effect of Frailty and Age in patients undergoing Vestibular
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Frailty may be more accurate for predicting surgical outcomes and leading treatment decisions than patient's age alone following vestibular schwannoma (VS) resection, according to a study by JAMA Otolaryngology-Head & Neck Surgery.

The aim was to conduct a population-based evaluation of the independent associations of chronological age and frailty (physiological age) with outcomes following VS resection.

In this large-scale, multicenter, cross-sectional analysis, weighted discharge data from the National Inpatient Sample were searched to identify adult patients who underwent VS resection from 2002 through 2017. Among the 27?313 patients identified for VS resection, the mean age was 50.4 years, 15?031 were women, and 4720 were of non-White race/ethnicity. Of the included patients, 15?090 were considered robust, 8204 were prefrail, 3022 were frail, and 996 were severely frail.

Results:
--On univariable analysis, increasing frailty was associated with the development of postoperative hemorrhagic or ischemic stroke, while increasing age was not.

--Following multivariable analysis, increasing frailty and non-White race/ethnicity were independently associated with both mortality and extended hospital stays while increasing age was not.

--Increasing frailty and non-White race/ethnicity were all independently associated with routine discharge.

In this cross-sectional study, findings suggest that frailty may be more accurate for predicting outcomes and guiding treatment decisions than advanced patient age alone following VS resection.

Source: https://jamanetwork.com/journals/jamaotolaryngology/article-abstract/2779390
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