Effectiveness of Remineralization Agents on the prevention o
This study shows that remineralization agent prior to in-office bleaching reduces tooth sensitivity. It was published in the International Journal of Dental Hygiene.

A total of 64 volunteers were randomly divided into four groups. Before undergoing in-office bleaching with 38% hydrogen peroxide gel, clinicians applied a placebo gel (control group), casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), neutral sodium fluoride gel (NSF), or nano-hydroxyapatite solution (n-HAP) on all buccal surfaces of teeth.

The gel was left undisturbed for 4 minutes. The efficacy of tooth whitening was assessed by determining the color change using SGU. Patients recorded their tooth sensitivities on the VAS scale.

Overall, there was no significant difference in shade change between the groups. Control and CPP-ACP groups showed significantly higher rates of hypersensitivity than NSF and the n-HAP group.

Conclusively, the use of a remineralization agent (n-HAP/NSF) before in-office bleaching did not affect the bleaching efficacy but did reduce tooth sensitivity. The before bleaching treatment use of an n-HAP solution can be suitable for reducing bleaching born sensitivity as well as commonly used NSF remineralizing gel before in-office tooth bleaching can reduce tooth sensitivity, the most common side effect associated with this procedure.

Source: https://doi.org/10.1111/idh.12524
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